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Classification   Symptoms

This section is edited by: Markus Dahlem, PhD

Pathology and Pathophysiological Mechanisms of Migraine Aura

This scections starts contrasting the different theories about the origin of the aura. It follows a detailed documentation of computer models that help to understand this complex phenomenon.

Neural vs Vascular Theory of Migraine Aura

Migraine study with functional Magnetic Resonanz Imaging

Migraine study with functional magnetic resonance imaging. © 2001 PNAS (cited from Hadjikhani et al. 2001)

Whether migraine aura has a neural or vascular cause is a current dispute in the literature of migraine pathology. [more]

Modelling Migraine Aura

Model of fortification pattern

Model of fortification pattern by Markus Dahlem. © 2004 Progress in Neurobiology (cited from Dahlem and Chronicle, 2004)

Neural networks and nonlinear dynamics can help to explain what happens to the brain during an migarine with aura. It is hoped that this computational neuroscience approach provides a new route to migraine etiology. [more]

References

Dahlem MA, Chronicle EP. Computational perspective on migraine aura. Prog Neurobiol 2004; 74: 351-361.
Hadjikhani N, Sanchez Del Rio M, Wu O, Schwartz D, Bakker D, Fischl B, Kwong KK, Cutrer FM, Rosen BR, Tootell RB, Sorensen AG, Moskowitz MA. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA 2001; 98: 4687-4692.

Author: Markus Dahlem
Last modification of this page: Tuesday January 31. 2006

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